Title: Data set of CA1 pyramidal cell models using an intact whole hippocampus preparation

Type Dataset Carey Y.L. Huh, Katie A. Ferguson, Bénédicte Amilhon, Sylvain Williams, Frances K. Skinner (2014): Data set of CA1 pyramidal cell models using an intact whole hippocampus preparation. Zenodo. Dataset. https://zenodo.org/record/8747

Authors: Carey Y.L. Huh (Douglas Mental Health University Institute) ; Katie A. Ferguson (Toronto Western Research Institute/University of Tornonto) ; Bénédicte Amilhon (Douglas Mental Health University Institute) ; Sylvain Williams (Douglas Mental Health University Institute) ; Frances K. Skinner (Toronto Western Research Institute/University of Toronto) ;

Links

• Item record in Zenodo
• Digital object URL

Summary

The frequency-current (f-I) profiles of pyramidal cells are presented. Each .abf file contains the f-I curve data for the respective cell (as labelled PYR1, PYR2, PYR3 and PYR4 for Pyramidal cell 1, Pyramidal cell 2, Pyramidal cell 3 and Pyramidal cell 4).  That is, they contain the cell's response to the application of a series of depolarizing current steps of 1 s duration while the cells are held in current clamp, as well as the current clamp data itself.  Each recording is 2 s total.  Amplitudes of the input were increased incrementally with step sizes of 10 pA for PYR1, PYR3, and PYR4, and a step size of 25 pA for PYR 2.  PYR1 first spikes on the 5th of 30 steps with 38.7 pA of depolarizing input.  PYR2 first spikes on the 3rd of 13 steps with 1.2 pA of input.  PYR3 first spikes on the 7th of 34 steps with 62.0 pA of input, and PYR4 first spikes on the 7th of 30 steps with 12.1 pA of input.

More information

• DOI: 10.5281/zenodo.8747

Subjects

• hyppocampus, pyramidal cells, frequency-current profile

Dates

• Publication date: 2014
• Issued: April 28, 2014

Rights

• https://creativecommons.org/publicdomain/zero/1.0/legalcode Creative Commons Zero v1.0 Universal
• info:eu-repo/semantics/openAccess Open Access

Format

electronic resource

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