This is a limited proof of concept to search for research data, not a production system.

Search the MIT Libraries

Title: Time series of epileptic seizures in a 8yo male on a cannabidiol trial

Type Dataset Barry, Dwight (2014): Time series of epileptic seizures in a 8yo male on a cannabidiol trial. Zenodo. Dataset. https://zenodo.org/record/8672

Author: Barry, Dwight ;

Links

Summary

Time series of epileptic seizures in a 8yo male with idiopathic catastrophic epilepsy (probably of mitochondrial origin) in a cannabidiol (CBD) trial.

The data are of observed seizures during each day by the patient's parents and caregivers and thus are not exact values for total daily seizure activity; the values in this dataset are best considered a lower bound. However, observation effort was essentially constant over the time series, so the data likely reflect overall trends even though precise daily seizure counts are not available.

The time series includes a 21-day baseline period and a 36-day trial period. The CBD was administered via g-tube in an olive oil base. Dosage was approximately 7.5 mg/kg/day for two weeks, and approximately 8 mg/kg/day for three weeks.

Each 1ml of oil contained 10.00mg of total CBD and 0.42mg of total THC, for a CBD:THC ratio of approximately 20:1 (analysis by HPLC).

Data Dictionary

Date: YYYY-MM-DD Tonic: tonic seizure count (http://www.epilepsy.com/learn/types-seizures/tonic-seizures) Tonic-Clonic: tonic-clonic (aka "grand mal") seizure count (http://www.epilepsy.com/learn/types-seizures/tonic-clonic-seizures) Spasms: myoclonic seizure count (http://www.epilepsy.com/learn/types-seizures/myoclonic-seizures) Total: total number of seizures (sum of above) Notes: notes by parents

More information

  • DOI: 10.5281/zenodo.8672

Subjects

  • pediatric epilepsy, cannabidiol, medical marijuana, mitochondrial disorder, time series dataset

Dates

  • Publication date: 2014
  • Issued: April 24, 2014

Rights


Much of the data past this point we don't have good examples of yet. Please share in #rdi slack if you have good examples for anything that appears below. Thanks!

Format

electronic resource

Relateditems

DescriptionItem typeRelationshipUri
IsPartOfhttps://zenodo.org/communities/zenodo