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Title: pc4covid19/pc4covid19: Version 4.1: Jupyter notebook (nanoHUB) COVID19 app

Type Software Randy Heiland, Paul Macklin (2020): pc4covid19/pc4covid19: Version 4.1: Jupyter notebook (nanoHUB) COVID19 app. Zenodo. Software. https://zenodo.org/record/4290732

Authors: Randy Heiland (Indiana University) ; Paul Macklin (Macklin cancer simulation lab) ;

Links

Summary

pc4covid19 - COVID19 (SARS-CoV-2) tissue simulator nanoHUB app

Version: 4.1

Release date: 25 November 2020

Overview

This repository contains code and data for the nanoHUB app https://nanohub.org/tools/pc4covid19. Here, we primarily report on changes to the app's GUI.

It is based on the model at https://github.com/pc4covid19/COVID19. Refer to that repository for a summary of changes to the model.

Caveats and disclaimers:

This model is under active development using rapid prototyping:

It has not been peer reviewed. It is intended to drive basic scientific research and public education at this stage. It cannot be used for public policy decisions. It cannot be used for individual medical decisions.

This model will be continually refined with input from the community, particularly experts in infectious diseases. The validation state will be updated as this progresses.

Release summary: 4.1:

Bug fix: Cell Types custom_data were not setting/getting values to/from XML.

4.0:

Updates to the core model. The Cell Types tab now shows "flattened" versions of the cell types, instead of the hierarchical version in v3. The Out:Plots tab now has an additional "Extra analysis" plot and provides a dropdown menu of options. The widgets have been rearranged to accommodate. The Animate tab has been removed.

3.2:

Updates to the core model; nothing new in the GUI.

3.1:

Minor updates to About text, e.g., explaining nature of stochastic results. Edits to immune_submodels.cpp (see details in the core model repository).

3.0:

The major change to the GUI in this release is the addition of a 'Cell Types' tab. This allows editing parameters associated with <cell_definitions> in the configuration file.

This version also includes a <style> block in the Jupyter notebook that fixed an unwanted scrollbar in the lengthy About tab.

2.0:

The major change to the GUI in this release is the addition of an 'Animate' tab. This allows animation of cells (not substrates) in the tab and the generation of a .mp4 video that can be downloaded. The animation uses the cells' SVG files.

1.0:

Provides a "standard" PhysiCell-based Jupyter notebook GUI consisting of 5 tabs:

About: a description of the model and the app Config Basics: input parameters common to all models (e.g., domain grid, simulation time, choice/frequency of outputs) Microenvironment: microenvironment parameters that are model-specific User Params: user parameters that are model-specific Out: Plots: output display of cells and substrates

More information

  • DOI: 10.5281/zenodo.4290732

Dates

  • Publication date: 2020
  • Issued: November 25, 2020

Rights

  • info:eu-repo/semantics/openAccess Open Access

Much of the data past this point we don't have good examples of yet. Please share in #rdi slack if you have good examples for anything that appears below. Thanks!

Format

electronic resource

Relateditems

DescriptionItem typeRelationshipUri
IsSupplementTohttps://github.com/pc4covid19/pc4covid19/tree/v4.1
IsVersionOfhttps://doi.org/10.5281/zenodo.3750175
IsPartOfhttps://zenodo.org/communities/covid-19
IsPartOfhttps://zenodo.org/communities/zenodo