Title: Genetic variability at the catalytic site of the SARS-CoV-2 RNA MTase NSP16 and the predicted effects of mutations on SAM and RNA binding
Type Other Yazdani, Setayesh, Schapira, Matthieu, Nicola De Maio (2020): Genetic variability at the catalytic site of the SARS-CoV-2 RNA MTase NSP16 and the predicted effects of mutations on SAM and RNA binding. Zenodo. Other. https://zenodo.org/record/3897734
Links
- Item record in Zenodo
- Digital object URL
Summary
In this document, we explain the methods of predicting the effect of genetic variability at the catalytic site of the SARS-CoV-2 RNA MTase NSP16 on SAM and RNA binding. The PDF document contains the detailed methods which accompany the following posts on https://openlabnotebooks.org/.
The Druggability of SARS-CoV-2 NSP16, the SAM-dependent m7GpppA-specific 2’-O-methyltransferase - Post 5 Mapping the genetic variations of Alpha- and Betacoronavirus UniProt entries onto SARS-CoV-2 NSP16 crystal structure – Post 6 Genetic variability at the catalytic site of the SARS-CoV-2 RNA MTase NSP16 and predicted effects of mutations on SAM and RNA binding - Post 7 Predicting the effect of all possible mutations at the 39 sidechains of NSP16 catalytic site on SAM and RNA-binding - Post 8The energy_matrix_NSP16.icb contains the ICM script for the post 8 above.
More information
- DOI: 10.5281/zenodo.3897734
Dates
- Publication date: 2020
- Issued: June 17, 2020
Rights
- https://creativecommons.org/licenses/by/4.0/legalcode Creative Commons Attribution 4.0 International
- info:eu-repo/semantics/openAccess Open Access
Format
electronic resource
Relateditems
| Description | Item type | Relationship | Uri |
|---|---|---|---|
| IsVersionOf | https://doi.org/10.5281/zenodo.3897733 | ||
| IsPartOf | https://zenodo.org/communities/covid-19 | ||
| IsPartOf | https://zenodo.org/communities/openlabnotebooks | ||
| IsPartOf | https://zenodo.org/communities/zenodo |