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Title: DrosophilaMuscleFunction: Revised Submission to Scientific Reports

Type Dataset Hatfield, Isabelle, Harvey, Innocence, Yates, Erika R, Redd, JeAnna R, Reiter, Lawrence T, Bridges, Dave (2014): DrosophilaMuscleFunction: Revised Submission to Scientific Reports. Zenodo. Dataset. https://zenodo.org/record/13367

Authors: Hatfield, Isabelle (University of Tennessee Health Sciences Center) ; Harvey, Innocence (University of Tennessee Health Sciences Center) ; Yates, Erika R (University of Tennessee Health Sciences Center) ; Redd, JeAnna R (University of Tennessee Health Sciences Center) ; Reiter, Lawrence T (University of Tennessee Health Sciences Center) ; Bridges, Dave (University of Tennessee Health Sciences Center) ;

Links

Summary

This repository version corresponds to the bioRxiv preprint:

Hatfield I, Harvey I, Yates, ER, Redd, JR, Reiter LT, Bridges D (2014) The role of TORC1 in muscle development in Drosophila. bioRxiv. doi:10.1101/010991.

http://dx.doi.org/10.1101/010991

 

This version addressed the reviewer comments from the first round of submission. The relevant documents are here

Reviewer Comments: SREP Reviews Response to Reviewers: SREP Response Updated Manuscript: Manuscript

Relevant Changes

Added data regarding the effects of Mhc-GAL4 driven knockdown. This potentially late-acting driver had no effects on birth rates or climibing, but did have deleterious effects on the lifespan of the animals. This was done primarily in #19 and #18 . Tested role of fusion and expression of Myh proteins with rapamycin treatment. This was done primarily in #19 and #15 Evaluated protein stability of MyoD. We found that MyoD proteinwas degraded quickly with rapamycin treatment, but that the mRNA was unaffected. This was done in issue #16 Several other minor clarifications were also made in issue #17 and #14

More information

  • DOI: 10.5281/zenodo.13367

Subjects

  • development, drosophila, myogenesis, differentiation

Dates

  • Publication date: 2014
  • Issued: December 24, 2014

Rights

Much of the data past this point we don't have good examples of yet. Please share in #rdi slack if you have good examples for anything that appears below. Thanks!

Format

electronic resource

Relateditems

DescriptionItem typeRelationshipUri
IsSupplementTohttps://github.com/BridgesLab/DrosophilaMuscleFunction/tree/0.2.0
IsVersionOfhttps://doi.org/10.5281/zenodo.591714
IsPartOfhttps://zenodo.org/communities/zenodo