Title: Co-crystal structures of USP5 Zf-UBD and weak binding compounds
Type Dataset Mann, Mandeep, Harding, Rachel, Ravichandran, Mani, Edwards, Aled, Arrowsmith, Cheryl, Schapira, Matthieu (2018): Co-crystal structures of USP5 Zf-UBD and weak binding compounds. Zenodo. Dataset. https://zenodo.org/record/1313723
Links
- Item record in Zenodo
- Digital object URL
Summary
Determination of crystallization conditions which allow growth of well-diffracting co-crystals of USP5 zinc finger ubiquitin binding domain (Zf-UBD) and compounds shown to bind weakly by 19F NMR and SPR assays & to solve the co-crystal structures to determine if electron density of ligands can be seen in the binding pocket of the protein domain.
More information
- DOI: 10.5281/zenodo.1313723
Subjects
- usp5, crystallography, structure, zinc finger, xray
Dates
- Publication date: 2018
- Issued: July 17, 2018
Notes
Other: Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.Rights
- https://creativecommons.org/licenses/by/4.0/legalcode Creative Commons Attribution 4.0 International
- info:eu-repo/semantics/openAccess Open Access
Format
electronic resource
Relateditems
| Description | Item type | Relationship | Uri |
|---|---|---|---|
| IsVersionOf | https://doi.org/10.5281/zenodo.1313722 | ||
| IsPartOf | https://zenodo.org/communities/openlabnotebooks | ||
| IsPartOf | https://zenodo.org/communities/sgc-opennotebook | ||
| IsPartOf | https://zenodo.org/communities/zenodo |